Our latest work with the Hiesinger Lab got published in Science!

In an integrative experimental-computational work, we could unravel the intriguing mechanisms by which neuronal wiring in developing brains is achieved: We showed for the fly’s visual system that neuronal wiring is achieved by self-organisation during a process called ‘neural superposition’. While this process is inherently stochastic, it results in a robust formation of the fly’s visual map, i.e. ensuring that information from distinct receptors that point at the same visual axis are bundled at the post-synapsis. Interestingly, this process of axonal sorting during super-positioning is independent of target neurons (= hence a self-sorting/organizing mechanism). Article available here: https://doi.org/10.1126/science.adk3043